FOLIUM is a research project aimed at producing high-density liquid fuels in the green biomass of tobacco. By introducing genetic material from microorganisms and other plants, tobacco can synthesize hydrocarbon fuels in its leaves and stems. Also, tobacco can be engineered to increase efficiency of CO₂ uptake and solar energy capture. Coupled with improvements in agricultural practices, these approaches will increase the yield of fuel production in tobacco.  

Research efforts for FOLIUM, a Department of Energy, ARPA-E project under the PETRO (Plants Engineered to Replace Oil) Program, are conducted by researchers from Lawrence Berkeley National Laboratory, the University of California, Berkeley, and the University of Kentucky
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